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Bacterial Takeover Cheats, Tips, Tricks & Hints to Destroy the Universe

What do scorned scientists do when they are upset? Use their knowledge to wipe out all life on the planet, of course. Available on Android and iOS platforms, Bacterial Takeover lets you take on the role of one angry scientist who is on a mission to destroy every planet for no good reason. To do so, you will need to cultivate and develop bacteria that will obliterate all life. Start by taking over smaller planets. Those that are too weak to fight your biological attacks. As you develop stronger bacteria, you can move on to larger planets with inhabitants that have better infection resistance. You don’t just need stronger bacteria, you need a lot of them. Produce bacteria by the billions in order wipe out even the most resistant creatures! If you need find yourself struggling to move forward on your path of destruction, check out our Bacterial Takeover ultimate strategy guide for some help!

1. Aim For Complete Wipeouts

A common pitfall for new players in Bacterial Takeover is when they hesitate to use their full strength in an attack because they are worried about losing the bacteria that they have built up. What you need to remember is that the factories that you use to produce bacteria are the same facilities you will use to attack. There is no point in holding on to just some of them. Make sure you build up enough bacteria to wipe out the planet in a single attack.

If you fail to wipe out the planet in a single raid, you will essentially be setting back your progress because you will need to start over. The only benefit you will gain from this is that you will get additional gene strands, but that is hardly worth the work that has been wasted.

2. Prioritize Your Passive Income

Let’s face it, you will not be able to sustain active production for 24 hours a day. There is a good chance that you will be spending most of your time idle. That is why you should prioritize upgrading passive production over active ones. When you upgrade your passives, make sure you aim for the milestones as well. Hitting around 200% in each upgrade will boost the overall output by a lot. This will allow you to produce insane amounts of bacteria without exerting any effort.

3. Choose Gene Strand Upgrades Wisely

When you obliterate a planet, you will gain gene strands. Each one will give a 1% boost to your Bacteria Per Second. You can spend these strands to purchase gene strand upgrades. Just keep in mind that when you spend them, you will lose the 1% boost that they give you. Gene strand upgrades allow you to improve different production methods. However, you only have limited resources, so you cannot realistically upgrade everything without sacrificing efficiency. That is why you need to be smart in choosing your gene strand upgrades. If you followed our previous advice, you will know that the best investment when it comes to gene strands, is still passive income. Choose upgrades that will improve your bacteria per second. You want to improve this any way you can in order to produce the massive numbers that you will need in later stages of the game.

4. Research For 24 Hours

While it might be exciting to get quicker results from research, you will benefit a lot more if you are patient. There are several options for research time, and the success rate of each depends on how long it takes. The best option for you to choose is the 24-hour timeframe with a success rate of 50%. This gives you a good chance to discover new strands of DNA that will boost your production even more. Going for anything less than 50% is just too risky to waste your time on. It will most likely result in failure to discover any new strands.

5. If You Want To Be Active

Of course, if you really want to go the active route, there are also several options for you. This means you have a lot of time to tap on the screen like there’s no tomorrow. Make sure you purchase the Bacteria Gun colonies to make your active life a little easier. The Bacteria Gun colonies will increase your Bacteria Per Click, so you will be able to produce a lot without breaking your fingers. In terms of gene strand upgrades, you should also go for those that improve your Bacteria Per Click. It is all about investing in the upgrades that will help you in the play style that you choose. Read all the descriptions carefully and choose the ones that will benefit you the most.

6. Look For The Red Bacteria

Once in a while, when you are playing actively, you will see some red bacteria. Tap on the red bacteria as soon as you see it. This will give you random temporary boosts that will help you progress faster such as increased bacteria per second for some time. The catch is that you will sometimes be asked to watch a video advertisement in exchange for the boost. It only takes a few seconds to watch the video, so make sure you take advantage of it whenever you can. This will allow you to improve your production even more.

7. Watch Ads To Get Diamonds

Aside from the red bacteria advertisements that will allow you to gain temporary boosts, there is another use for ads in Bacterial Takeover. You can gain premium currency called diamonds by watching ads. Each advertisement will give you 5 diamonds. You will need 50 diamonds in order to unlock an extra scientist. Extra scientists will grant you better evolution research methods. At the cost of watching ten advertisements, this is definitely a great way to improve your bacteria production. Just keep watching ads until you have enough to unlock extra scientists. You don’t even need to actually watch. Just play the ad and do something else for a minute or so.

It is time to take over the universe in Bacterial Takeover! Just stick to our list of tips, cheats and tricks and you will be destroying galaxies in no time!


Friday 30th of July 2021

Everything that guy said at the bottom and to also remember to do the short times if you will be there for a second 5 chances is better than 1


Friday 24th of August 2018

After getting through the black hole several times, buying upgrades at black matter institute, researching a lot of upgrades, it actually takes you just a few hours to wipe the first 20-30 planets. Looking in hindsight, only the first round (until I entered the black hole) was difficult.

So what to do to advance faster? 1. keep your diamonds to only buy scientists. I currently have 15 and would like some extra: 8 of them are doing planetary research to get all the planetary bonuses from every planet (you need them after planet 50), 5 of them are getting a colony Iradiation ready in 2 hours, 5 of them are Evolving new bacteria, and 5 of them can get you 2000 nanobots while you sleep at night. 2. when you have dark matter, buy the passive skills for BPS production and research 3. Do Collony Irradiation all the time, the bonuses will stack and make your life easier. Then take advantage of your most irradiated colony (for me, it is the Rotting Fish and the Industrial Asteroid that are doing the hard work, I can buy ~6000 of them in the first 4-5 minutes at the current planet) 4. When buying colonies, try to get the big bonuses that come at every threshold of 1000. 5. Spend your gene strands to buy all the upgrades available, you will get that many that it doesn't matter if you save them. 6. Don't wait to wipe out a planet in one go. It doesn;t help you with anything, just eats your time. Buy colonies until you get stuck and it takes too long to buy another, and then look in the planetary attack screen at the percent of the population you can destroy. If you see that the percent is growing slower and slower (you wait more seconds to see it grow another 0.01%), attack the planet and start building colonies again. If you do this a couple of times, spending ~5 minutes buying colonies at every turn, you will get the population under 1% fast enough for the first 20-30 planets. When your population is under 1%, you can easily finish the planet with some nanobots. 7. Nanobots are only helpful when your population is lower, don't waste your scientists' time on nanobots until you get your population under 20-30%. 8. Don't forget that you can reduce research time with 1 hour watching an ad. Tap on the active research and you will see this option. You get to do this 2 times every 7 hours. 9. Evolve bacterias to lvl 4. They make a huge difference. Try to evolve superior bacterias (epic, legendary, mythical) to get huge boosts. Mix bacterias with similar rarity and similar bonuses that you want (mainly BPS, Idle bonus, Gene strands, Research time) to get huge bonuses. My best bacteria so far gives me +13mil% BPS, +81mil% Idle Bonus, +5400% Gene strands and -23% research time. Just to get an idea :) 10. I forgot: doing planetary research is not only giving you upgrades, it also gives you Minerals (they give you even more bonuses). You can fuse minerals to get other ones, for extra bonuses. After you fuse a mineral, you can find it again if you do Planetary research.

I read this article and comments few months ago, when I started and needed tips to grow faster. Looking back at it now, I realise that almost all the people writing advices were also beginners. I hope my tips will help you guys :)


Saturday 9th of June 2018

you can change your clock. Changing the time actually affect the game. also, daily log in, you can skip a day like that, until you reach a day where you get 50 gems, then you can start moving to previous days, and keep getting 50 gems


Thursday 5th of April 2018

Sorry for the late reply, hope sumone still reads this post. Any help on how many strands to try to keep on hand? Im on planet 8


Monday 9th of April 2018

I was purchasing only the passive bonus ones until planet 18... after that I had so many strands that it didnt matter if I wased few thousand. However I find myself stuck at planet 20 not being able to get even remotely close to the 100-something ee bacteria that I need for next colony. I guess im missing something


Wednesday 4th of April 2018

A common mistake is to build up only the newest colonies. Go do the first ones up to 1000 witch will give you 500000% boost on that colony